Table 1

Risk Factors for Development of Epithelial Ovarian Cancer

>50 years

Demographics Reproductive factors

Familial tendency Diet

Environmental exposure

White or European Jewish descent residence in industrialized nation (except Japan) Early menarche, late menopause Infertility Nulliparity

Breastfeeding, oral contraceptive use protective Family history BRCA1, BRCA2 mutation DNA mismatch repair gene mutation High fat intake High coffee intake Low fiber Low vitamin A Perineal talc use Asbestos Radiation Viral infection (rubella, mumps)

In this chapter, risk factors for ovarian cancer will be discussed, with an emphasis on hereditary ovarian cancer syndromes as well as screening and management options.

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