Conclusion

In conclusion, recent advances in molecular studies of trophoblastic cells in the normal placenta, implantation site, and in trophoblastic lesions have shown that the latter recapitulate the normal trophoblast in the early developing placenta and implantation site. This new knowledge, especially, the identification and characterization of the genes expressed in human trophoblast will help elucidate the pathogenesis of trophoblastic lesions, and will also provide a foundation to facilitate the pathological diagnosis of various types of trophoblastic tumors and tumor-like lesions.

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