Health care professionals continue to be concerned with the potential negative side effects of high dietary protein intake associated with low carbohydrate diets. Concerns include dehydration, fatigue, increased calcium excretion, colon cancer and increased renal burden . Additionally, high saturated fat intake and increased risk of heart disease are associated with low carbohydrate, high protein diets . Diabetics are one population in whom the use of low carbohydrate diets needs to be carefully monitored given the high incidence of renal disease . Some research has demonstrated a decrease in microalbuminuria with improvement in glycemic control  with no increase in serum creatinine concentrations ; however, few studies have directly addressed more sensitive markers of renal function such as the glomular filtration rate (GFR). Although the data suggests that at 6 months there is an improvement of co-morbid conditions among low-carbohydrate dieters, the potential for associated side effects needs to be further investigated.
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