As mentioned previously calcium and vitamin D appear to have chemo-preventive effects in the colon and rectum. Calcium appears to decrease colon epithelial hyperproliferation , while vitamin D seems to modulate the effects of calcium. Calcium binds secondary bile acids and ionized fatty acids [36-38] that stimulate epithelial cell proliferation of the colorectal mucosa . Initial studies of the impact of calcium on colorectal cancer risk were conflicting . The syner-gistic effect of vitamin D and calcium was elucidated in the Calcium Polyp Prevention Study where the benefits of calcium supplementation were observed only in individuals with high serum 25-hydroxy vitamin D levels . It appears that both nutrients are necessary for efficacy in polyp prevention.
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WHAT IT IS A three-phase plan that has been likened to the low-carbohydrate Atkins program because during the first two weeks, South Beach eliminates most carbs, including bread, pasta, potatoes, fruit and most dairy products. In PHASE 2, healthy carbs, including most fruits, whole grains and dairy products are gradually reintroduced, but processed carbs such as bagels, cookies, cornflakes, regular pasta and rice cakes remain on the list of foods to avoid or eat rarely.