16. What characteristics of bite wounds favor anaerobic infections?
17. What is the causative agent of cat scratch disease? Why is it a threat to patients with AIDS?
18. What is a synergistic infection? How might one be acquired?
19. What is Madura foot?
20. Why is sporotrichosis sometimes called rose gardener's disease? Multiple Choice
1. All of the following are true of Staphylococcus aureus, except
A. it is generally coagulase-positive.
B. its infectious dose is increased in the presence of a foreign body.
C. some strains infecting wounds can cause toxic shock.
D. nasal carriage increases the risk of surgical wound infection.
E. it is pyogenic.
2. Which of these statements about Streptococcus pyogenes is false?
A. It is a Gram-positive coccus occurring in chains.
B. Some strains infecting wounds can cause toxic shock.
C. Some strains infecting wounds can cause necrotizing fasciitis.
D. It can cause puerperal sepsis.
E. A vaccine is available for preventing S. pyogenes infections.
3. Choose the one false statement about Pseudomonas aeruginosa.
A. It is widespread in nature.
B. Some strains can grow in distilled water.
C. It is a Gram-positive rod.
D. It produces a hemolytic toxin having the same mode of action as /¡-toxin of Clostridium perfringens.
E. Under certain circumstances it can grow anaerobically.
Chapter 27 Wound Infections
4. Which of these statements concerning tetanus is true?
A. It can originate from a bee sting.
B. Immunization is carried out using tiny doses of tetanospasmin.
C. Those who recover from the disease are immune for life.
D. Tetanus immune globulin is derived from the blood of immunized sheep.
E. It is easy to avoid exposure to spores of the causative organism.
5. Choose the one true statement about gas gangrene.
A. There are few or no leukocytes in the wound drainage.
B. It is best to rely on antibacterial medications and avoid disfiguring surgery.
C. A toxoid is generally used to protect against the disease.
D. Only one antitoxin is used for treating all cases of the disease.
E. It is easy to avoid spores of the causative agent.
6. All the following statements about actinomycosis are t rue, except
A. it can occur in cattle.
B. it is caused by a branching filamentous bacterium.
C. it always appears on the jaw.
D. it can arise from intestinal surgery.
E. its abscesses can burrow into bone.
7. Which of the following statements about Pasteurella multocida is false?
A. Infections generally respond to a penicillin.
B. It can cause epidemics of fatal disease in domestic animals.
C. It is commonly found in the mouths of biting animals, including human beings.
D. A vaccine is in general use to prevent P. multocida disease in people.
E. Cat bites are more likely to result in P. multocida infections than dog bites.
8. Which of these statements about cat scratch disease is false?
A. It is a common cause of chronic lymph node enlargement in children.
B. It is a serious threat to individuals with AIDS.
C. Cat scratches are the only mode of transmission to humans.
D. It is a zoonosis of cats transmitted by fleas.
E. It can affect the brain or heart valves in a small percentage of cases.
9. The following statements about Streptobacillus moniliformis are all true, except
A. it can be transmitted by food.
B. its colonies can resemble those of mycoplasmas.
C. it can be transmitted by the bites of animals other than rats.
D. human infection is characterized by irregular fevers, rash, and joint pain.
E. it is a Gram-positive spore-forming rod.
10. Pick out the statement concerning sporotrichosis that is wrong.
A. It is characterized by ulcerating lesions along the course of a lymphatic vessel.
B. Person-to-person transmission is common.
C. It can occur in epidemics.
D. It can persist for years if not treated.
E. The causative organism is a dimorphic fungus.
1. Clinicians become concerned when the laboratory reports that organisms capable of digesting collagen and fibronectin are present in a wound culture. What is the basis of their concern?
2. ABC pharmaceutical company produces a drug that inhibits new blood vessel growth into cancers, thus depriving the cancer cells of the nutrients and hormones needed for growth of the tumor. A researcher in the company laboratory has now isolated a compound having the opposite effect. Do you see any possible role for the new compound in the treatment of wounds?
3. An army field nurse performing triage at a mobile surgical hospital asks this question of all the ambulance drivers: "Was the soldier wounded while in a pasture?" Why did he ask this question?
1. In what ways would the curve of tetanus incidence in an economically disadvantaged country differ from figure 27.11?
2. Could colonization of a wound by a noninvasive bacterium cause disease? Explain your answer.
3. Surgical wound infections are frequently due to Staphylococcus aureus, a bacterium often carried in the nostrils and sometimes on the skin. How would you study the relationship, if any, between carriage of S. aureus and the chance of getting a wound infection?
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