Radiation

Two kinds of radiation are mutagens: ultraviolet (UV) light and X rays. ■ wavelengths of radiation, p. 122

Ultraviolet Irradiation

Irradiation of cells with ultraviolet light causes covalent bond formation between adjacent thymine molecules on the same strand of DNA (intrastrand bonding), resulting in the formation of thymine dimers (figure 8.5). The covalent bonding distorts the DNA strand so much that the dimer cannot fit properly into

Normal nitrogenous base

Normal nitrogenous base

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