Prevention and Treatment

No proven preventive measures are known other than to avoid areas where soil is heavily enriched with bat, chicken, and bird droppings, especially if they have been left undisturbed for a long period. Some researchers have recommended that several inches of clay soil be placed over soils containing large quantities of old droppings. Treatment of histoplasmosis is similar to that of coccidioidomy-cosis. Amphotericin B and itraconazole are used for treating severe disease, but both medications have potentially serious side effects.

The main features of histoplasmosis are described in table 23.15.

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