Pathogenesis

Infectious conidia of H. capsulatum are inhaled with dust from contaminated soils and develop into the yeast form. The organisms promptly enter macrophages and grow intracellularly. Granulomas develop in infected areas, closely resembling those seen in tuberculosis, sometimes even showing caseation necrosis. Eventually, the lesions are replaced with scar tissue, and many calcify, meaning that the body deposits calcium compounds in them that show up on X rays. In rare cases, the disease is not controlled and spreads throughout the body. This suggests AIDS or other immunodeficiency.

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Bacterial Vaginosis Facts

Bacterial Vaginosis Facts

This fact sheet is designed to provide you with information on Bacterial Vaginosis. Bacterial vaginosis is an abnormal vaginal condition that is characterized by vaginal discharge and results from an overgrowth of atypical bacteria in the vagina.

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