Nucleic acid probes detect specific nucleotide sequences in a sample. Colony blots are used to identify colonies that contain a given sequence of DNA. Southern blots are used to determine the size of the restriction fragments that contain a sequence of interest and to detect subtle variations in nucleotide sequences that occur in different strains of a given species. Fluorescence in situ hybridization is used to observe cells in intact specimens that contain a given sequence. Nucleotide array technology enables a researcher to

9.2 Applications of Nucleic Acid Hybridization 227

Strain A DNA

Bacterial Vaginosis Facts

Bacterial Vaginosis Facts

This fact sheet is designed to provide you with information on Bacterial Vaginosis. Bacterial vaginosis is an abnormal vaginal condition that is characterized by vaginal discharge and results from an overgrowth of atypical bacteria in the vagina.

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