Microcheck 243

The pathogenesis of tooth decay depends on both dietary sucrose and acid-forming bacteria that are adapted to colonize hard, smooth surfaces within the mouth. Periodontal disease is a chronic condition, caused by plaque at the gum margin, that can lead to loosening of teeth. Trench mouth is an acute illness with destruction of gingival tissue. Chronic infection by Helicobacter pylori is a key factor in the development of gastric and duodenal ulcers and gastric cancer.

■ What enzyme produced by Heliobacter pylori assists its survival in stomach acid?

■ A sucrose-rich diet is important in tooth decay, but figure 24.4 shows the effect of glucose. Are sucrose and glucose equivalent? Why or why not?

■ Discuss the pros and cons of the statement "Helicobacter pylori causes stomach cancer."

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