Microcheck 223

Extensive skin damage can result from a toxin absorbed into the circulation from a localized infection. An immunological reaction to circulating microbial products can damage the kidneys. Changes in the skin in an infectious disease commonly reflect similar changes in other body tissues. Zoonoses involving ticks and small mammals pose a widespread danger to humans. Complex ecological factors can govern the incidence of infectious diseases.

■ List four extracellular products of Staphylococcus aureus that contribute to its virulence.

■ Describe the characteristic rash of Lyme disease.

■ The existence of extensive scalded skin syndrome does not indicate that Staphylococcus is growing in all the affected areas. Why?

Figure 22.16 Life Cycle of the Black-Legged Tick, Ixodes scapularis, the Principal Vector of Borrelia burgdorferi, Cause of Lyme Disease Note that the life cycle covers 2 years, during which the tick obtains three blood meals.The males die soon after mating, the females after depositing their eggs in the following spring.Variations in the life cycle occur, probably dependent on climate and food availability.

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