Microcheck 186

Autoimmune disease can result when the immune system reacts to substances of self. Autoimmune diseases cover a spectrum from organ-specific to generalized. They are treated with drugs that suppress immune or inflammatory responses. Attempts are being made to induce specific tolerance to the causative substances.

■ How could viruses or bacteria be implicated in causing autoimmune diseases?

■ Explain what is meant by the spectrum of autoimmune diseases, from organ-specific to generalized.

■ How would semipermeable membranes protect transplanted pancreas cells?

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