Microcheck 169

Mechanisms used to generate the diversity of antigen specificity in lymphocytes include rearrangement of gene segments, imprecise joining of those segments, and combinatorial associations of heavy chains and light chains. Negative selection eliminates B cells and T cells that recognize normal "self" molecules. Positive selection permits only those T cells that show moderate recognition of the MHC molecules to develop further.

■ What three gene segments encode an antibody molecule?

■ What are autoantibodies?

■ How could imprecise joining be considered a type of frameshift mutation?

Detox Diet Basics

Detox Diet Basics

Our internal organs, the colon, liver and intestines, help our bodies eliminate toxic and harmful  matter from our bloodstreams and tissues. Often, our systems become overloaded with waste. The very air we breathe, and all of its pollutants, build up in our bodies. Today’s over processed foods and environmental pollutants can easily overwhelm our delicate systems and cause toxic matter to build up in our bodies.

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