Microcheck 165

In response to antigen, only those lymphocytes that recognize the antigen proliferate. This process gives rise to a population of clones of the original cell. Depending on their developmental stage, lymphocytes may be referred to as immature, naive, activated, effector, or memory cells.

■ Describe the clonal selection theory.

■ How does a naive lymphocyte differ from an activated one?

■ If the heavy chain of an antibody consists of four domains, each approximately 110 amino acids long, how much DNA would be required to encode 109 separate heavy chain genes?

Chapter 16 The Adaptive Immune Response

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