Interferons induce cells in the vicinity of a virally infected cell to prepare to cease protein synthesis should they become infected with virus. Double-stranded RNA functions as the signal to a cell that it is infected with a virus.
■ What activities does interferon gamma have that interferons alpha and beta do not?
■ What is the source of interferon that is used therapeutically?
■ Considering that retroviruses have an RNA genome, why would their replication not generate double-stranded RNA?
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