Microcheck 157

Inflammation is a cascade of events initiated in response to invading microbes or tissue damage. The outcome is dilation of small blood vessels, leakage of fluids from those vessels, and migration of leukocytes out of the bloodstream and into the tissue. Inflammation can help contain an infection, but the response itself can cause damage. Apoptosis provides a mechanism for the destruction of self-cells without initiating inflammation.

■ Describe three general events that can initiate inflammation.

■ Describe the changes that characterize cells that are undergoing apoptosis.

■ How could infection of the fallopian tubes lead to sterility and ectopic pregnancy?

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