Microcheck 155

Toll-like receptors enable cells to detect molecules that signify the presence of a microbe. Complement proteins can be activated by three mechanisms, leading to opsonization, lysis of foreign cells, and inflammation.

■ What is the role of C3b in opsonization?

■ What is the role of C3b in complement activation?

■ Why would the discovery of toll-like receptors alter the view that innate immunity is non-specific?

384 Chapter 15 The Innate Immune Response

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