Toll-like receptors enable cells to detect molecules that signify the presence of a microbe. Complement proteins can be activated by three mechanisms, leading to opsonization, lysis of foreign cells, and inflammation.
■ What is the role of C3b in opsonization?
■ What is the role of C3b in complement activation?
■ Why would the discovery of toll-like receptors alter the view that innate immunity is non-specific?
384 Chapter 15 The Innate Immune Response
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