Lumen Of Stomach

Helicobacter pylori

Mucus layer

Stomach-lining epithelium

Basement membrane

Connective tissue

Epithelium destroyed by gastric acid

Helicobacter pylori

Epithelium destroyed by gastric acid

Mucus layer

Stomach-lining epithelium

Basement membrane

Connective tissue

Mucus-secreting cell

Red blood cell

Capillary

Figure 24.8 Gastric Ulcer Formation Associated with Helicobacter pylori Infection Thinning of the protective layer of mucus probably results from an inflammatory and immune response to the bacteria growing on or near the epithelium.The acid and pepsin of the stomach juices can then attack the epithelium. Neutrophils are phagocytic early responders to inflammation; lymphocytes and plasma cells represent the immune response.

Neutrophil

Plasma cell

Red blood cell Ulcer

Dilated capillary

Mucus-secreting cell

Red blood cell

Capillary

Figure 24.8 Gastric Ulcer Formation Associated with Helicobacter pylori Infection Thinning of the protective layer of mucus probably results from an inflammatory and immune response to the bacteria growing on or near the epithelium.The acid and pepsin of the stomach juices can then attack the epithelium. Neutrophils are phagocytic early responders to inflammation; lymphocytes and plasma cells represent the immune response.

Neutrophil

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