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Figure 8.7 Repair of Thymine Dimers (a) In light repair, a light-requiring enzyme breaks the two covalent bonds (photoreactivation). (b) In dark, or excision, repair, the single strand of DNA containing the thymine dimer is removed and destroyed.The newly synthesized strand is joined to the end of the original strand by the enzyme DNA ligase. Light is not required.

Covalent bonds

Thymine dimer results in a distortion of the sugar-phosphate backbone.

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