The repressor is synthesized as a form that alone cannot bind to the operator. When a molecule, termed a corepressor binds to it, however, its shape is altered so that it can bind to the operator, blocking transcription initiation.
The repressor is synthesized as a form that effectively binds to the operator, blocking transcription initiation. The binding to it of a molecule that functions as an inducer, alters the shape of the repressor so that it no longer binds to the operator. Consequently, the gene can be transcribed.
Promoter (with RNA polymerase)
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