Influenza virus, an orthomyxovirus
@ Newly formed virions bud from infected cells, they are released by viral neuraminidase and infect ciliated epithelium, mucus-secreting, and alveolar cells.
Infection of respiratory epithelium; cells destroyed and virus released to infect other cells. Secondary bacterial infection results from damaged mucociliary escalator
@ Infected cells ultimately die and slough off; recovery of the mucociliary escalator may take weeks.
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