Figure 6.16 The Transition Step and the Tricarboxylic Acid Cycle The transition step links glycolysis and the TCA cycle, converting pyruvate to acetyl-CoA; it generates reducing power and 1 precursor metabolite.The TCA cycle incorporates the acetyl group of acetyl-CoA and using a series of steps, releases CO2; it generates ATP, reducing power in the form of both NADH and FADH2, and 2 different precursor metabolites.

Step 2: A chemical rearrangement occurs.


Step 3: CO2 is removed and an oxidation generates NADH.


Step 4: An oxidation generates NADH, CO2 is removed, and coenzyme A is added. \ NADH + H+

Step 5: The energy released when CoA is removed is harvested to produce ATP.

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