Malignant hyperthermia (MH) is a potentially fatal genetic myopathy inherited in an autosomal dominant fashion. It is asymptomatic until triggered by either a non-depolarizing muscle relaxant and/or potent inhalational vapors used in anesthesia. The incidence of an MH reaction varies from 1: 6,000 to 1: 40,000 anesthetics. In the past, a fulminant MH crisis was virtually fatal; however now mortality is less than 5%. The decrease in mortality is due to improved education of patients and operating room personnel, improvements in anaesthetic monitoring and the availability of dantrolene.

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