Which organ systems

A valid measure of organ dysfunction in critical illness must reflect the process as the clinician understands it or, in methodological terms, it must have construct validity. Thus the first step in the development of the MOD score was to understand multiple organ dysfunction syndrome as it is perceived by the clinician. A systematic review of the literature describing multiple organ dysfunction syndrome identified 30 papers published between 1969 and 1993, and is described in detail elsewhere (Marshall 1995).

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