Treatment

Treatment is mainly symptomatic and supportive. However, complications must be anticipated and treated speedily. All symptomatic cases should be observed for at least 6 h and can be discharged once they have become asymptomatic. Patients with evidence of moderate or severe toxicity or unstable vital signs must be admitted and may require intensive monitoring (Linden eta[ 1985).

After stabilizing the patient, gastrointestinal decontamination should be considered. Emesis is contraindicated as convulsions can set in rapidly. Although vagal stimulation from gastric lavage may precipitate seizures or cardiac arrhythmias, lavage should be performed in the stable patient within 2 h of ingestion of more than 2 mg/kg body weight. Activated charcoal avidly binds amphetamine and 50 g (10-15 g for a child) should be given orally or by narrow-gauge tube.

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