Treatment of central nervous oxygen toxicity

Breathing 100 per cent oxygen for a prolonged period is toxic to the lung and brain. To avoid oxygen toxicity during hyperbaric oxygen therapy regimens, there should be intermittent breaks for air breathing (Fig, 1). Symptoms of central nervous oxygen toxicity, such as a grand mal seizure, are treated by immediate removal of the oxygen mask. In the case of a seizure the chamber pressure should be kept constant until seizure activity ceases in order to avoid a pulmonary overpressure accident. Anticonvulsant therapy is usually unnecessary because termination of oxygen breathing stops seizure activity. Recurrent seizures are rare and patients usually recover without sequelae (Ki.z.e.L.199.5).

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