The steroid crisis is the result of too rapid an increase in steroid dosage at the start of steroid therapy ( Seybold and Dia.c.h.m..an 1974; Johns 1987). The patient can rapidly become weak and unresponsive to anticholinesterase therapy. The safe procedure is to manage the patient in the intensive care unit. If indicated, the patient should be intubated and ventilated until the situation improves. Usually the crisis has resolved and remission started within Z to 10 days.
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