Selective decontamination

Nosocomial pneumonia is commonly preceded by colonization of the oropharynx by Gram-negative aerobes. Selective digestive decontamination (SDD) may use an oral antifungal agent (e.g. amphotericin B) and two non-absorbable antibiotics, such as tobramycin and polymyxin B, given both as an oral paste and by mouth. Rapid reduction in the Gram-negative flora is ensured by administration of a systemic antibiotic, usually cefotaxime, for the first 4 to 5 days. Although some trials have suggested that SDD prevents both nosocomial pneumonia and mortality, few were placebo controlled or blinded. Double-blind placebo-controlled trials show reductions in the number of episodes of pneumonia, urinary infection, and sinusitis, but usually not in mortality or costs ( Si!v®L.a..n.d Bone 1993). Surprisingly, emergence of resistant bacteria during SDD is either rare or not easily demonstrated.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

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