Rifampin is a bactericidal antibiotic which inhibits protein synthesis by binding RNA polymerase. It is highly active against staphylococci, Corynebacteria, Moraxella species, Legionella species, and most strains of Mycobacterium tuberculosis. Resistance will emerge rapidly if it is used in isolation. Rifampin is distributed throughout the body and is excreted through the liver. It is a first-choice agent in treating tuberculosis and Mycobacterium avium intracellulare complex disease. In staphylococcal endocarditis, rifampin may be used in combination with a glycopeptide with or without an aminoglycoside. Fever, rash, and hepatotoxicity are the most important adverse effects. The antibiotic antagonizes the effects of warfarin, cyclosporin, verapamil, and oral hypoglycemics.

Healthy Fat Loss For A Longer Life

Healthy Fat Loss For A Longer Life

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