Reye's syndrome is a rare disorder which results in non-icteric hepatic encephalopathy. It occurs primarily in children and adolescents; predisposing factors include a variety of viral infections and the use of aspirin. Pathological changes include acute brain swelling and fatty infiltration of the liver and other visceral organs. In cases where acute cerebral edema is adequately controlled, complete recovery is usually attained. Continuous intracranial pressure monitoring is indicated in cases with neurological deterioration or high serum ammonia levels (above 300 ^g per cent (175 ^mol/l)) ( Chi eta[ 1990).
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