Response to edrophonium

Edrophonium (Tensilon®) is a short-acting anticholinesterase which can be administered intravenously. In myasthenia gravis a transient improvement in muscle strength occurs within 30 s of the administration of 4 to 8 mg of edrophonium. The effect only lasts for about 60 s. A positive response may not be seen in a myasthenic patient treated with anticholinesterase drugs if the patient is in a cholinergic state. In fact such a patient can be made considerably worse by the test. A patient on anticholinesterase therapy should be pretreated with intravenous atropine first to prevent a bradycardia, and resuscitation facilities should be available when performing the test.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

Get My Free Ebook


Post a comment