Pulmonary hypertension

Pulmonary hypertension has been described in up to 15 per cent of patients with SLE, although usually it is not clinically significant. The pathology of pulmonary hypertension is not well understood, since vasculitis of the pulmonary vasculature is rarely seen. The role of recurrent pulmonary thromboembolism and antiphospholipid antibody syndrome should be considered among the major etiologies of pulmonary hypertension. Other potential mechanisms responsible include a chronic hypoxic state due to interstitial fibrosis and the chronic alveolar hemorrhage syndrome. Clinically, pulmonary hypertension in SLE is analogous to primary (idiopathic) pulmonary hypertension. Raynaud's phenomenon is common. The secondary form of pulmonary hypertension caused by chronic and recurrent pulmonary emboli can be treated by pulmonary thromboembolectomy. Thus diagnostic tests including pulmonary angiography should be considered. The prognosis in those with persistent pulmonary hypertension is grave. Response to vasodilator therapy is unsatisfactory.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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