Pancuronium

This synthetic steroid-based non-depolarizing agent has negligible ganglion-blocking activity and is devoid of histamine-releasing potential. It is potent and has a relatively long duration of action. There is a small rise in heart rate (by a combination of vagal inhibition and sympathetic stimulation) and the blood pressure is maintained. It has been a popular mainstay in the ICU for many years. Since it is metabolized in the liver and eliminated via the kidneys, its action is prolonged in patients with liver and/or renal impairment. It is safer to use pancuronium by intermittent bolus doses than by infusion. The level of block should be measured regularly in order to guard against cumulation.

Healthy Fat Loss For A Longer Life

Healthy Fat Loss For A Longer Life

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