Oxygen debt as the underlying cause of organ failure and death

The basic underlying problem in all shock is tissue hypoxia which can be measured as the net cumulative oxygen debt. If this oxygen debt is prevented or corrected early on, there will be a reduction in organ failure and death. Oxygen debt can be determined directly in surgical patients by measuring oxygen consumption preoperatively and, after correcting for the effects of anesthesia and temperature, extrapolating this value to the intraoperative and immediate postoperative periods.

Oxygen debt due to reduction of Vo2 to a level less than that needed by the body is the common denominator in all forms of shock. Oxygen debt from reduced Vo2 is also the major determinant of outcome.

Healthy Fat Loss For A Longer Life

Healthy Fat Loss For A Longer Life

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