Other causes of acute intrinsic renal failure

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Other less common etiologies of ARF include acute allergic interstitial nephritis, characterized by inflammatory cell infiltration and interstitial edema. It is typically induced by antibiotics (penicillins, cephalosporins, and sulfonamides), diuretics (hydrochlorothiazide), non-steroidal anti-inflammatory drugs, allopurinol, and angiotensin-converting enzyme inhibitors (captopril). Renal artery or vein occlusion and glomerulonephritis may also reduce glomerular filtration rate and generate ARF, the etiology of which is often suspected by the clinical setting.

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