Multiple physiological insults

Another important finding is that combined or sequential physiological insults produce more injury than a single insult. In animal models, gut ischemia-reperfusion causes pulmonary leak and neutrophil sequestration but little morbidity or mortality; independently, the injection of a low dose of endotoxin causes neutrophil sequestration but no leak. However, the same dose of endotoxin given after reperfusion results in acute lung injury and a high mortality. This type of pattern is much more typical of the clinical situation, where relatively minor disturbances of physiology, many of them iatrogenic, may occur repeatedly following a major precipitant such as trauma, surgery, or cardiopulmonary arrest.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

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