Key messages

• The therapeutic use of intravenous immunoglobulin is limited to certain imunological disorders such as immune thrombocytopenic purpura and Guillain-Barre syndrome. No conclusive benefit has been demonstrated in patients with sepsis and septic shock.

• The side-effects of intravenous immunoglobulin are immune complex formation, increased immunoglobulin levels, and infection transmission.

• Monoclonal antibodies against lipid A and tumor necrosis factor-a, interleukin 1 receptor antagonist, and platelet activating factor antagonist have not demonstrated a survival benefit in phase III clinical trials of patients with septic shock.

• The administration of murine monoclonal antibodies leads to the production of human anti-mouse antibodies.

• Granulocyte colony-stimulating factor augments neutrophil number and function and reduces infectious complications during myeloablative chemotherapy.

• There are no convincing data for the use of colony-stimulating factors in critically ill patients with pneumonia and septic shock.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

Get My Free Ebook


Post a comment