Key messages

• Benzodiazepines are the drugs most frequently involved in acute poisoning.

• Benzodiazepine overdose usually has a good prognosis:

most patients do well with only careful observation and prevention of complications;

supportive care including intubation, ventilation, and fluid administration may be required in some cases.

• Care should be taken with the following:

• elderly people, patients with chronic obstructive pulmonary disease, or liver disease;

• short-acting compounds;

• association with other central nervous system depressants.

• Flumazenil is a useful diagnostic tool and may help to improve alertness and prevent the need for respiratory support in some patients. Introduction

Benzodiazepines have a wide pharmacological profile (namely hypnosedative, anxiolytic, muscle relaxant, amnestic, and anticonvulsant properties) and a high therapeutic index. They have replaced most older hypnosedatives, particularly barbiturates, in clinical use. Abuse potential has been recognized more recently.

Was this article helpful?

0 0
Healthy Fat Loss For A Longer Life

Healthy Fat Loss For A Longer Life

What will this book do for me? A growing number of books for laymen on the subject of health have appeared in the past decade. Never before has there been such widespread popular interest in medical science. Learn more within this guide today and download your copy now.

Get My Free Ebook


Post a comment