Key messages

• Pre-eclampsia, a multisystem disorder characterized by systemic hypertension and proteinuria, is a major cause of maternal death.

• Abnormal placentation is central to the pathogenesis of pre-eclampsia; there is failure of endovascular trophoblast invasion of the myometrial segments of spiral arteries.

• Endothelial dysfunction precedes clinical hypertension and accounts for the pathological changes seen in various organs.

• Uncontrolled lipid peroxidation and deportation of syncytiotrophoblast basement membrane elements from the placenta may mediate endothelial dysfunction.

• Neutrophil and platelet activation occurs, although this is probably secondary to endothelial dysfunction.

Healthy Fat Loss For A Longer Life

Healthy Fat Loss For A Longer Life

What will this book do for me? A growing number of books for laymen on the subject of health have appeared in the past decade. Never before has there been such widespread popular interest in medical science. Learn more within this guide today and download your copy now.

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