Key messages

• Respiratory stimulant effects are exhibited by a number of different classes of drugs, the most significant of which are the analeptics (doxapram and nikethamide), theophylline, and the triazine derivatives (almitrine bismesylate).

• The place of doxapram in respiratory failure remains contentious, but it may have a role where non-invasive mechanical support is impractical.

• Theophyllines have a theoretical role in the treatment of respiratory failure but await large-scale clinical trials in this context.

• Almitrine bismesylate is an orally active respiratory stimulant with potential in the treatment of both acute and chronic respiratory failure.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

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