Key messages

• The main advantage of inhalational sedation is pulmonary excretion and rapid recovery.

• The effective sedative dose of isoflurane is 0.1 to 0.4 per cent.

• Isoflurane is only 0.2 per cent metabolized and can be used safely in patients with renal or hepatic failure.

• Isoflurane causes bronchial relaxation in patients with bronchospasm and is an ideal sedative for ventilated patients with severe asthma and chronic obstructive pulmonary disease.

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