Key messages

• Myasthenia gravis is an autoimmune disease which causes muscle weakness.

• The anti-acetylcholine receptor antibody causes a marked reduction of acetylcholine receptor density in the post-junctional membrane.

• There is a reduction in the safety margin for neuromuscular transmission which accounts for the fatiguable muscle weakness.

• Symptomatic improvement in muscle power can occur with anticholinesterase medication.

• Removal of the thymus gland often produces a reduction in anti-acetylcholine receptor antibody and an improvement in symptoms. Introduction

Myasthenia gravis is a disorder of neuromuscular transmission. The disease is brought about through the action of a circulating antibody which dramatically reduces the density of acetylcholine receptors on the postjunctional membrane of the neuromuscular junction ( New,s,om:iDavisii1992; Drachman 1994).

Kicking Fear And Anxiety To The Curb

Kicking Fear And Anxiety To The Curb

Kicking Fear And Anxiety To The Curb Can Have Amazing Benefits For Your Life And Success. Learn About Calming Down And Gain Power By Learning Ways To Become Peaceful And Create Amazing Results.

Get My Free Ebook

Post a comment