Key messages

• Acute hepatic failure is seen in patients with acute hepatic necrosis whose clinical course is complicated by the development of encephalopathy and coagulopathy.

• Metabolic derangements, including hypoglycemia, hypophosphatemia, and metabolic acidosis, are frequently seen.

• There is a high incidence of renal failure and hemodynamic disturbance, usually with a hypotensive, hyperdynamic state.

• Management is supportive in the first instance. Most patients are significantly volume depleted and require aggressive volume resuscitation.

• The level of consciousness can change rapidly. Patients who deteriorate to grade III coma should be electively ventilated because of the risk of cerebral edema and to allow optimal treatment.

• Consideration should always be given to liver transplantation; in selected patients the mortality with medical treatment alone remains at 90 per cent.

Kicking Fear And Anxiety To The Curb

Kicking Fear And Anxiety To The Curb

Kicking Fear And Anxiety To The Curb Can Have Amazing Benefits For Your Life And Success. Learn About Calming Down And Gain Power By Learning Ways To Become Peaceful And Create Amazing Results.

Get My Free Ebook


Post a comment