Key messages

• Acute respiratory failure is the final common pathway of many pulmonary and extrapulmonary pathologies.

• Coexisting disease influences the assessment of acute respiratory failure. A pan-systemic approach is an important aspect of management.

• Augmentation of oxygenation and carbon dioxide clearance are therapeutic goals.

• Ventilation is indicated where acute respiratory failure is not responsive to continuous positive airways pressure (CPAP) or oxygen therapy alone, or where the use of CPAP is inappropriate.

• All modes of positive-pressure ventilation aim at maximizing alveolar recruitment by increasing mean airway pressure. Avoiding high peak-inspiratory pressures and large tidal volumes reduces the risk of barotrauma and volotrauma.

• Normal arterial blood gases may not be appropriate targets in severe acute respiratory failure.

• Patient posture may influence the degree of ventilation-perfusion mismatch

• Inhaled nitric oxide or nebulized prostacyclin may improve oxygenation and ameliorate pulmonary hypertension.

• Early CT scanning in acute respiratory failure indicates the nature and degree of pulmonary involvement and influences management strategy.

Healthy Fat Loss For A Longer Life

Healthy Fat Loss For A Longer Life

What will this book do for me? A growing number of books for laymen on the subject of health have appeared in the past decade. Never before has there been such widespread popular interest in medical science. Learn more within this guide today and download your copy now.

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