Key messages

• Aprotinin is a naturally occurring non-specific serine protease inhibitor.

• The major role of aprotinin in critical care practice is the prevention of bleeding associated with extracorporeal circulations.

• Life-threatening bleeding due to thrombolytic therapy may be arrested by the plasmin inactivation effect of low-dose aprotinin.

• In septic shock and hepatic cirrhosis, high-dose aprotinin may improve hypotension and organ perfusion.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

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