Key messages

• Meningitis should be treated with cefotaxime or ceftriaxone.

• Ceftazidime or piptazobactam are appropriate for treatment of ventilator-associated pneumonia more than 2 days after intubation.

• Teicoplanin is less likely to cause nephrotoxicity than vancomycin when used in combination with aminoglycosides.

• Imipenem and meropenem should not be used in combination with other b-lactams.

• Clindamycin is the drug of choice in aspiration pneumonia.

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