Key messages

• The new classification of acute liver failure (ALF) takes into account rapidity of onset and etiology as important indicators of likely progress.

• Microcirculatory dysfunction with covert tissue oxygen debt is the basis of multiple organ failure.

• Host defenses to bacterial infection are severely compromised early in the course of ALF.

• Reduction in cerebral blood flow and resultant cerebral ischemia are important in the development of cerebral edema.

• Acetaminophen (paracetamol) overdose is the most common cause of ALF in the United Kingdom. Antituberculosis drug therapy is responsible for an increasing number of cases.

• The frequency with which viral hepatitis A, B, C, D, E is the cause of ALF is related to the underlying prevalence of these infections in the country concerned. In many cases of presumed fulminant viral hepatitis, no specific agent is identifiable.

Was this article helpful?

0 0
Kicking Fear And Anxiety To The Curb

Kicking Fear And Anxiety To The Curb

Kicking Fear And Anxiety To The Curb Can Have Amazing Benefits For Your Life And Success. Learn About Calming Down And Gain Power By Learning Ways To Become Peaceful And Create Amazing Results.

Get My Free Ebook

Post a comment