Key messages

• The major advantage of continuous renal replacement therapy (CRRT) is the excellent hemodynamic tolerance.

• Continuous pump-driven (venovenous) renal replacement therapy has largely replaced arteriovenous techniques because of the access-related complications and limited efficacy of the latter.

• The need for continuous anticoagulation is the weak point of CRRT.

• Indications for CRRT are acute renal failure with severe fluid overload, hemodynamic instability, cerebral edema, or the need for adequate nutritional input.

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