Key messages

• Acute mountain sickness is associated with relative hypoventilation in relation to high-altitude hypoxia, water and sodium retention, and endothelial cell activation with increased capillary permeability.

• The severity of symptoms correlates with the degree of hypoxemia.

• Possible pathogenetic factors for the development of high-altitude cerebral edema include a depletion reduction in the active outward sodium transport, hydrostatic edema due to the increase in cerebral blood flow, a decrease in intracranial compliance, and hypoxia-induced angiogenesis and osmotic swelling.

• High-altitude pulmonary edema may be due to overperfusion, high permeability, or mechanical damage to pulmonary endothelial and epithelial cells.

Sleep Apnea

Sleep Apnea

Have You Been Told Over And Over Again That You Snore A Lot, But You Choose To Ignore It? Have you been experiencing lack of sleep at night and find yourself waking up in the wee hours of the morning to find yourself gasping for air?

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