Key messages

• Transfusion of wrong blood does occur in the intensive care unit.

• Irradiate blood for severely immunodeficient patients or blood from a first-degree relative.

• Transfuse with caution in conditions of hyperviscosity.

• If O RhD-negative blood is used in an emergency, switch to ABO- and RhD-compatible blood as soon as possible.

• In massive transfusion, give fresh frozen plasma and platelets according to clinical and laboratory indices, not fixed prophylactic replacement formulas. Introduction

The aim of treatment of anemia is to ensure an adequate oxygen supply to the tissues. Oxygen delivery depends on cardiac output and arterial oxygen content, which in turn depends on hemoglobin concentration and oxygen carried per gram of hemoglobin ( Mollison eta], 1994).

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